Endodermal sinus tumor of the vagina in a child.

نویسندگان

  • Anuradha Dhanasekharan
  • Anne George Cherian
  • Paul Emmanuel
  • Kaushal Patel
چکیده

Malignant germ cell tumors are rare tumors of the childhood accounting for less than 3 % of pediatric malignancies. Endodermal sinus tumor (EST) is the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs [1]. They are usually diagnosed before 3 years of age. Historically, the approach to therapy has included radical surgical resection with adjuvant irradiation and chemotherapy [2]. We report a case of EST of the vagina which was managed conservatively with chemotherapy alone.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

YOLK SAC TUMOR OF VAGINA

   Malignant germ-cell tumors (MGCT) are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumor (EST) forms the most common histologic subtype of MGCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. She was pale and a mass was palpab...

متن کامل

Endodermal Sinus Tumor of Vagina in Infants

Endodermal sinus tumor (or Yolk Sac tumor) of the vagina is a rare malignant germcell tumor which is seen exclusively in children younger than 3 years of age. We report two cases of endodermal sinus tumor of the vagina. In both cases no radiological investigation was done and serum alpha-fetoprotein was elevated. The histopathological examination of both the tumor masses revealed vaginal endode...

متن کامل

Metrorrhagia in a child with an endodermal sinus tumor of the vagina: a case report.

In a female child presenting with vaginal bleeding or a mass protruding through the vagina, it is mandatory to perform an endoscopic and laparoscopic examination and biopsy to establish the correct diagnosis and precise extent of the lesion. An endodermal sinus tumor (EST) of the vagina is a rare, malignant germ cell tumor that occurs primarily in infants. Clearly, the vagina is a critical site...

متن کامل

Endodermal sinus tumor of the vagina--a rare entity treated exclusively with chemotherapy.

Endodermal Sinus Tumor (EST) is the rarest of the vaginal tumors. It commonly occurs in children of under 3 years and usually presents with vaginal bleeding EST is most frequently encountered in the ovary. It is exceedingly rare in the vulva. Approximately 50 cases of EST of the vagina or uterine cervix have been reported. The presence of Schiller Duval bodies and various histologic patterns ch...

متن کامل

Lectin affinity electrophoresis in a yolk sac tumour in the vagina with yolk sac tumour-type glycoform of alpha fetoprotein.

AIMS To investigate a potential diagnostic use of alpha fetoprotein (alpha FP) isoform analysis by lectin affinity electrophoresis to distinguish between endodermal sinus tumours arising in the vagina in infants from those at other sites. METHODS alpha FP in the serum of a patient with a vaginal endodermal sinus tumour was analysed for its isoforms by lectin affinity electrophoresis. The isof...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of obstetrics and gynaecology of India

دوره 62 Suppl 1  شماره 

صفحات  -

تاریخ انتشار 2012